Successful Treatment of Acquired Amegakaryocytic Thrombocytopenia (AAT) with Cyclosporine and Eltrombopag: A Case Report
نویسندگان
چکیده
منابع مشابه
Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).
Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease mediated by a deregulated immune system and aberrant production of proinflammatory cytokines leading to multiorgan and tissue damage. Thrombocytopenia is a common complication in patients with SLE, with a prevalence that ranges from 7–30%.1-5 The 2 main mechanisms of thrombocytopenia in SLE are increased platelet de...
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Acquired amegakaryocytic thrombocytopenic purpuria (AATP) is an unusual hematologic disorder characterized by thrombocytopenia resulting from an unexplained reduction in the number of bone marrow megakaryocytes in the presence of otherwise normal hematopoiesis in the bone marrow [1]. The exact prevalence of acquired amegakaryocytic thrombocytopenia is unknown due to its very rare incidence. Aro...
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Treatment of chronic, severe refractory immune thrombocytopenia after splenectomy is difficult. Only less data exist on clinical use of cyclosporine A (CyA) in the management of refractory ITP. In this report, we describe two cases in which standard immunosuppressive therapy, other immunosuppression including cyclosporine A or splenectomy had no therapeutic effect. Even after splenectomy, recom...
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Introduction: Aluminum phosphide is one of the most common causes of poisoning in the country. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. It mainly attacks the cardiovascular and respiratory systems. Eating even small amounts of this toxin can lead to death. This study reports a case of successful treatme...
متن کاملSuccessful Treatment of Aluminium Phosphide Poisoning: A Case Report
Aluminium phosphide (AlP) is used to kill rodents in grain storage. It produces phosphine gas which is toxic for mitochondria. The exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. This poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...
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ژورنال
عنوان ژورنال: Journal of Hematology and Blood Disorders
سال: 2018
ISSN: 2455-7641
DOI: 10.15744/2455-7641.4.101